Blunted Expansion of Regulatory Tlymphocytes Is Associated With Increased Bacterial Translocation in Patients With Major Depressive Disorder

Major Depressive Disorder (MDD) is associated with both proinflammatoryand adaptive immune response abnormalities. Regulatory T lymphocytes (Tregs), asubtype of CD4+ T cells, are relevant for maintaining immune-inflammatory systemhomeostasis and control of inflammation such as the kind potentially induced by theinteractions between the intestinal microbiome and gut mucosa. We investigated theTreg population and its distribution along […]